POLYMER CHEMISTRY

Members


Nathalie Götting (NG)	Rigo Herrmann (RH)	Hans Fritz (HF)


Xiao-Ning Liu (XL)	W. Schumann

Synthesis and functionalization of monodisperse polymer particles in the µm-size range (HF, XL)
Application of monodisperse polymerbeads in HPLC, catalysis, solid phase peptide- and nucleotide synthesis (HF, XL)
Preparation of polystyrene poly(etyleneimine) graft copolymers and derivatives (XL)
Characterization of surface-modified crosslinked polystyrene beads via FT-IR and CP/MAS- NMR (XL)
Preparation of colloidal drug carrier systems for DNA-fragments and gene-transfer (HF, NG)
Characterization of polymer colloids (REM, PCS, conductometric titration, zeta potential, etc.) (HF, NG)
Synthesis of polyoxyethylene and polyethyleneimine graft copolymers and derivatives (RH)

Group of Prof. Dr. D. Oelkrug (Institute of Physical Chemistry,Tuebingen)
Group of P.D. Schrenk (Tuebingen): Antisense mdr with primer hepatocytes
Group of Prof. H. Kalthoff (Kiel): gene transfer using plasmid-nanospheres-conjugates p53
Fa. Coulter Electronics:

E. Bayer, X. N. Liu, U. Tallarek, A. Ellwanger, K. Albert, M. Kutubuddin: "Polystyrene-Immobilized Poly(ethyleneimine) Chains. A New Class of Graft Copolymers", Polymer Bulletin 37
X. N. Liu, E. Bayer, G. Xue: "Infrared Quantitative Study of Acetylation of Microspheres of Polystyrene", Spectroscopy Letters 30
W. Rapp, H. Fritz, E. Bayer: "Monosized Grafted Microspheres for Ultra High Speed Peptide Synthesis (HSPS)" in Peptides: Chemistry and Biology, Proceedings of the American Peptide Symposium, 12th, Ed. by John A. Smith and Jean E. Rivier, ESCOM Science Publishers, Leiden 1992, S. 529.
M. Eggenweiler, N. Clausen, L. Zhang, H. Fritz, E. Bayer: "Comparative Studiese of Mono- and Polydisperse Polystyrene and Polystyrene-Polyethyleneglycol Graft Copolymer Beads" in Peptides 1994 (Proceedings of the 23nd European Peptide Symposium, Braga, Portugal 1994), Ed. by H. Maia, ESCOM Science Publishers, Leiden 1995
B. Lehr, H-J. Egelhaaf, H. Fritz, W. Rapp, E. Bayer, D. Oelkrug: "Molecular Solvation and Mobility in Polymer/Liquid Interphases. A Fluorescence Study on Polystyrene-Poly(ethylene glycol)", Macromolecules 29
H. Fritz, M. Maier, E. Bayer: "Cationic Polystyrene Nanoparticles: Preparation and Characterization of a Model Drug Carrier System for Antisense Oligonucleotides", J. Colloid Interface Sci. (submitted).

E. Bayer, H. Fritz, M. Maier: "Herstellung von biologisch aktiven Nanopartikel-Nucleinsäure-Konjugaten zur Anwendung in der Antisense-Strategie und zum Gen-Transfer" , Deutsches Bundespatent, angemeldet am 23.10.1996.

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